The carbon group of resin acids is lipophilic, affecting the lipids in cell membranes and increasing the cell membrane permeability. It was hypothesized that paraformaldehyde penetrates the sinus through overfilled sealer and may cause tissue irritation and local necrosis of the sinus mucosa. Histological analysis of the healing of intentional root perforations repaired with MTA (Holland et al. Other properties that have been investigated include antibacterial effects (Torabinejad et al. If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. R.G. Articles from 1942-2009 (Oct 2014) were considered. • materials used in dentistry come into direct contact with the hard tissues of teeth, the oral mucosa, the pulp & the periapical tissues. In vivo studies have demonstrated that Sealapex and CRCS easily disintegrate in the tissue (Soares et al. Objectives: In dentistry, application of different materials in long-term oral usage demands low or nontoxic agents gains importance for both patients and the staff. Keywords: Biocompatibility; dental materials; composite resin. Azar et al. 2001) and as such should not pose a problem. 1999, Ersev et al. 1995). Biocompatibility Evaluation of Biodentine in Subcutaneous Tissue of Rats. Review articles on biocompatibility were included.  |  1988, Boiesen & Brodin 1991, Bezerra et al. Schweikl et al. Dorn & Gartner (1990) showed that root‐end fillings with two versions of zinc oxide–eugenol had a significantly higher success rate than with amalgam. Within the groups of (co)monomers and (co)initiators, high or moderate cytotoxic reactions were observed. International Journal of Occupational Medicine and Environmental Health. A long‐term histological study, Apical leakage after root canal filling with an experimental calcium hydroxide gutta‐percha point, The periapical tissue reactions to a calcium phosphate cement in teeth of monkeys, Cytotoxicity of resin‐, zinc oxide–eugenol‐, and calcium hydroxide‐based root canal sealers on human periodontal ligament cells and permanent V79 cells, An analysis of the release and the diffusion through dentin of eugenol from zinc oxide–eugenol mixtures, Long‐term results of amalgam versus glass ionomer cement as apical sealant after apicectomy, The mutagenic potential of AH+ and AH26 by, Methylmethacrylate monomer produces direct relaxation of vascular smooth muscle, Determination of the toxicity of root‐canal‐filling materials and their separate components in cell cultures, Asymptomatic aspergillosis of the maxillary sinus associated with foreign body of endodontic origin, Formaldehyde release from root‐canal sealers: influence of method, Formaldehyde release from dental materials, Experimental study of the biocompatibility of a new glass ionomer root canal sealer (Ketac‐Endo), Influence of zinc oxide and eugenol sealer on concentration of zinc, calcium and copper in rat tissues, Cytotoxicity of three resin‐based root canal sealers implanted into the subcutaneous connective tissue of rats, Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations, Release of formaldehyde by 4 endodontic sealers, Tissue response to an epoxy resin‐based root canal sealer, Calcium hydroxide root canal sealers – histopathologic evaluation of apical and periapical repair after endodontic treatment, Formaldehyde in dentistry: a review of mutagenic and carcinogenic potential, Genotoxicity and cytotoxicity of the epoxy resin‐based root canal sealer AH Plus, Cytotoxicity of root perforation repair materials, Iodoform gutta percha: MGP, a new endodontic paradigm, A study of long‐term toxicity of endodontic materials with use of an, Histologic evaluation of the biocompatibilty of Diaket [Abstract #716], Leakage of amalgam and Super‐EBA root‐end fillings using two preparation techniques and surgical microscopy, Subcutaneous implantation in the biological evaluation of endodontic material, Intraosseus implantation for biological evaluation of endodontic materials, Early tissue reaction to endodontic filling materials, Histopathology and X‐ray microanalysis of the subcutaneous tissue response to endodontic sealers, Effect of addition of hydroxyapatite on the physical properties of IRM, Release of formaldehyde from dental composites, Retrograde root filling with EBA cement or amalgam. 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